Enhancement of Loperamide Dissolution Rate by Liquisolid Compact Technique
نویسندگان
چکیده
منابع مشابه
Enhancement of Loperamide Dissolution Rate by Liquisolid Compact Technique.
Purpose: The aim of present study was to improve the dissolution rate of poorly soluble drug Loperamide (LPM) by liquisolid compact technique. Methods: Liquisolid compacts of LPM were prepared using Propylene glycol (PG) as a solvent, Avicel pH 102 as carrier, Aerosil as coating material and Sodium Starch Glycolate (SSG) as superdisintegrant. Interactions between the drug and excipients were ex...
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Lovastatin is a poorly soluble, BCS class II drug belonging to the category of anti-hyperlipidemics having poor bioavailability (<5%).The present study is designed to enhance the dissolution rate and bioavailability of Lovastatin by Liquisolid compacts and to evaluate the effect of carriers on drug dissolution rates. Lovastatin Liquisolid tablets were prepared by using different carriers namely...
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ژورنال
عنوان ژورنال: Advanced Pharmaceutical Bulletin
سال: 2016
ISSN: 2228-5881,2251-7308
DOI: 10.15171/apb.2016.050